Insulin dependent diabetes

Diabetes Mellitus (diabetes) is a chronic disease in which the body is unable to make sufficient insulin and/or is unable to utilize effectively the insulin it produces.

Type I (insulin-dependent) diabetes is an autoimmune condition in which the insulin-producing (beta) cells of the pancreas are destroyed by the body’s immune system; it accounts for 5-10% of all cases of diabetes in the US. Type II diabetes is characterized by insulin resistance, in which tissues are unable to respond to insulin effectively. Eventually, insulin production fails in type 2 diabetes as well, leading to the need to replace insulin by injection or infusion.

Approximately 29 million patients have Type I Diabetes worldwide and currently require life-long insulin therapy. Furthermore, Type II Diabetes — the more common form of diabetes with more than 200 million diagnosed patients worldwide — also frequently necessitates insulin therapy.

Currently, 50% of patients in the US who are diagnosed with diabetes fail to meet their glycemic (blood sugar) goal. Diabetes remains a leading cause of kidney disease, blindness, painful neuropathy, non-traumatic amputation, cardiovascular disease and early mortality. The estimated global economic burden of diabetes is $1.3 trillion per year and continues to rise.

Advantages of Forkhead solution

Better control

No need to worry about variations in …

  • Food
  • Sleep
  • Exercise
  • Travel
  • Health

Which may lead to poor control, and complications such as …

  • Heart attack
  • Blindness
  • Kidney failure
  • Amputation
  • Mortality

Easier patient experience

  • Orally administered drug
  • No more injections,
    meters, devices or tubes